15 comments

  • danielrmay 17 minutes ago
    Bravo. I feel like there's a kind of growth that only arrives through pain, but I wish nobody had to receive it that way.

    Peering through the NICU window & wondering if my child would survive was one of the most traumatizing moments of my life. Rooting for your work.

  • KennyBlanken 1 minute ago
    Really gotta love people who trauma-dump with no appropriate boundaries.
  • teruakohatu 12 minutes ago
    That story is heart breaking. I really feel for you and your family. I quite literally cannot imagine having to make that decision regardless of how inevitable it was, and how much pain you felt.

    No matter how short his life, or how much his suffering, Owen did get to experience being held by parents who loved him.

  • myzek 9 minutes ago
    My first son will be born in 2 months and I must say, between stories like this and others that I learned in antenatal classes - I have never been more terrified in my life
  • data_maan 38 minutes ago
    Aside from the sad life events, little information is shares about his "system", the thing HN is interested in.

    Is this more than a harness built on top of a SOTA commercial LLM?

  • jdw64 51 minutes ago
    This is such a sad story. What would it feel like to have a child? I'll probably never experience it in my lifetime. I've never been through that, but when my sibling died of cancer, I couldn't do anything for nearly a year. I imagine it's a similar feeling. I wish you all the best in everything you do from now on.
  • croisillon 16 minutes ago
    > anti-natal communitarianism of SF

    oh boy

  • fabbbbb 55 minutes ago
    It reads like a specific genome would lead to deterministic outcomes. It does not. Life is messy.

    Most Down Syndrome people have happy lives, some can even leave alone and have an independent daily live.

    Life expectancy is up to 60 years.

    Yet in Iceland „Democratization“ of genetic diagnosis lead to basically 0% Down Syndrome kids.

    Where does this stop? What with someone of a genetic indication of aggressive cancer- life expectancy 55? Abort?

    The same (detectable) genetic mutation leads to vastly different lives.

  • epsteingpt 3 hours ago
    This is a heartbreaking story and you can't imagine a more motivated founder.

    Godspeed.

  • LoganDark 1 hour ago
    Huh.

    > It was clear that something about my approach was interesting.

    But no approach. Not even a hint.

    I do hope it pans out. I do understand it must be a trade secret in order for you to have a business, but I'm still a little underwhelmed.

    • andai 1 hour ago
      llm("opus", genome)
  • ungreased0675 4 hours ago
    I’m skeptical that general purpose LLMs are a good fit for a very specialized medical analysis task. Something trained specifically for the task would be the path I’d explore.
    • throwaw12 0 minutes ago
      > I’m skeptical that general purpose LLMs are a good fit for a very specialized medical analysis task

      If they can save more lives without harming other lives I would gladly take it during the analysis. Even saving 1% more lives is an amazing achievement!

    • dools 1 hour ago
      Does it say anywhere that he’s using general purpose models for the analysis? Fine tuning open weight models is generally available for pretty minimal cost, I’d say his reference to vibe coding is how he is building the software not how the software functions.
    • boxed 2 hours ago
      General models are very cheap to get started with though. So even if they are less than ideal, you can use them to get a company going and then make something more efficient.
  • aaronphilip03 1 hour ago
    You'll are extremely strong. Rooting for you'll!
  • tedesign 1 hour ago
    This is extremely disturbing.
    • vasco 1 hour ago
      Man tries to find way to improve situation that gave him needless distress surrounding the death of his newborn.

      Internet reply: this is extremely disturbing

    • PierceJoy 1 hour ago
      In what way?
      • senectus1 1 hour ago
        lots of different ways, the loss of a child the potential loss of two children, the powerlessness and despair the parents would have been feeling... turning to AI which might have a positive outcome but many of us are not very trusting of the tool.

        Its a sad story. I wish them well, I hope this is one of those scenarios that AI works exactly as desired.

        • bkmq 9 minutes ago
          [dead]